Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker BEFREE Taken together, these results suggest that DNMTs could be an effective factor in development of tamoxifen resistance in breast tumors. 30359738

2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression BEFREE We demonstrate that breast tumor xenografts in rats exposed to dLAN and circadian MLT disrupted express elevated levels of phosphorylated and acetylated STAT3, increased DNMT1, but reduced sirtuin 1 (SIRT1) and ARHI. 31077613

2019
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker BEFREE To evaluate the contribution of DNMTs expression and their promoter methylation as diagnostic biomarkers in development of breast malignancy and tamoxifen resistance, the present study was designed and 107 breast tumors and normal breast tissues were recruited. 29574992

2018
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker CTD_human Long non-coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR-152. 28544374

2017
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression BEFREE Disruption of STAT3-DNMT1 interaction by SH-I-14 induces re-expression of tumor suppressor genes and inhibits growth of triple-negative breast tumor. 29137356

2017
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker CTD_human Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers. 22520950

2012
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 Biomarker LHGDN Inhibition of histone deacetylases promotes ubiquitin-dependent proteasomal degradation of DNA methyltransferase 1 in human breast cancer cells. 18505931

2008
Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.360 AlteredExpression LHGDN Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer. 15755728

2005