Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.030 GeneticVariation BEFREE In addition to confirming known associations, a systemic lupus erythematosus-associated risk variant at TNXB was also associated with CKD attributed to type 1 diabetes (p = 2.5 × 10<sup>-</sup><sup>7</sup>), a membranous nephropathy-associated variant at HLA-DQA1 was also associated with CKD attributed to systemic lupus erythematosus (p = 5.9 × 10<sup>-</sup><sup>6</sup>), and an IgA risk variant at HLA-DRB1 was associated with both CKD attributed to granulomatosis with polyangiitis (p = 2.0 × 10<sup>-4</sup>) and to type 1 diabetes (p = 4.6 × 10<sup>-11</sup>). 29066732

2017

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.030 Biomarker BEFREE HLA DRB1*03 was found at reduced frequency in HCV antibody positive compared to HCV antibody negative CKD patients on regular dialysis (corrected p was not significant). 23391249

2013

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.030 GeneticVariation BEFREE In a previous case series, four Thai subjects with chronic kidney disease and Ab-positive PRCA were reported to have the HLA-DRB1*9 allele. 18370845

2008