Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2354
Gene Symbol: FOSB
FOSB
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.040 GeneticVariation BEFREE Activator Protein-1 (AP-1) transcription factors are most likely to be associated with malignant transformation in prostate cancer. 28386843

2017
Entrez Id: 2354
Gene Symbol: FOSB
FOSB
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.040 Biomarker BEFREE Moreover, morusin inhibited TPA-induced activator protein-1 (AP-1) and nuclear factor-kappa B (NF-κB) activation, which can mediate cell proliferation and malignant transformation. 28108223

2017
Entrez Id: 2354
Gene Symbol: FOSB
FOSB
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.040 AlteredExpression BEFREE The proto-oncogene c-Jun is a component of activator protein-1 (AP-1) transcription factor complexes that regulates processes essential for embryonic development, tissue homeostasis and malignant transformation. 24632621

2015
Entrez Id: 2354
Gene Symbol: FOSB
FOSB
CUI: C1608408
Disease: Malignant transformation
Malignant transformation 		0.040 AlteredExpression BEFREE We previously demonstrated a reduction in basal AP-1 transcriptional activity associated with the malignant transformation of human bronchial epithelial (HBE) cells that was, in part, a consequence of decreased c-fos expression. 9662337

1998