Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 Biomarker BEFREE PEITC may induce G0/G1 cell-cycle arrest through affecting the proteins such as cdk2, cyclin E, and p21 in GBM 8401 cells. 26678675

2017
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 Biomarker BEFREE Thus, two distinct RNA-based mechanisms activate this novel KAP/ROCK2/Cdk2-dependent invasion pathway in glioblastoma. 24704824

2015
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 AlteredExpression BEFREE It targets CDK2, 7 and 9 preferentially, which are also overexpressed in glioblastoma. 26151768

2015
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 Biomarker BEFREE Further analysis showed that NRAS and CDK2 were positively related with GBM. 24967941

2014
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 GeneticVariation BEFREE CDKN2 deletions occurred in GBM from patients somewhat older than those patients with GBM lacking CDKN2 deletion (mean age 53 vs. 48 years). 9217972

1997
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 GeneticVariation BEFREE Using a comparative multiplex PCR assay, homozygous deletions of the CDKN2/p16 gene were detected in 5 anaplastic astrocytomas (25%) and 6 GBMs (46%), but in none of the lower-grade tumors. 8857999

1996
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 GeneticVariation BEFREE Thirty-six of 42 GBMs (86%) had alterations of either CDKN2/p16 (n = 22), RB (n = 10), or both (n = 4); these two genetic changes, however, were relatively exclusive (P = 0.003). 8548755

1996
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 Biomarker BEFREE These data support a role for MTS1/p16/CDKN2 as a tumor suppressor gene in the in vivo evolution of GBMs. 7887443

1995
Entrez Id: 1017
Gene Symbol: CDK2
CDK2
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.380 GeneticVariation UNIPROT