Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 AlteredExpression BEFREE The expression of DECR1 and POLR2F was significantly lower, while the levels of HDAC1 and PDIA3 were highly expressed in GBM tissues. 31633244

2020
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 AlteredExpression BEFREE The expression level of GLS2 and related NADPH production capacity is associated with the regional heterogeneity of 5-ALA fluorescence in GBM. 28939850

2017
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 AlteredExpression BEFREE IDH1 silencing in GBM cells reduced levels of NADPH, deoxynucleotides, and glutathione and increased their sensitivity to radiation-induced senescence. 27923831

2017
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 AlteredExpression BEFREE Nox4 NADPH oxidase is abundantly expressed and has proven to be a major source of ROS production in glioblastoma. 24868315

2014
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 Biomarker BEFREE NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in glioblastoma multiforme. 22713363

2012
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 AlteredExpression BEFREE IDH activity was the main provider of NADPH in human normal brain and glioblastoma, but its role was modest in NADPH production in rodent brain and other tissues. 21527585

2011
Entrez Id: 1666
Gene Symbol: DECR1
DECR1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.070 Biomarker BEFREE The total NADPH production capacity in glioblastoma was provided for 65% by IDH activity and the occurrence of IDH1 (R132 ) mutation reduced this capacity by 38%. 20127344

2010