Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.340 Biomarker BEFREE Jagged1 is the ligands of the Notch signaling and has been shown to promote glioma-initiating cells (GICs) in glioblastoma. 30580328

2018

Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.340 AlteredExpression BEFREE Mouse DLL4 or JAG1 expressed in glioblastoma cells decreased tumour cell proliferation in vitro but promoted tumour growth in vivo. mDLL4-expressing tumours showed fewer but larger vessels whereas mJAG1-tumours produced more vessels. 28445154

2017

Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.340 AlteredExpression BEFREE Here, we show that EGFR expression correlates with JAGGED1 expression in glioblastoma patients. 25514871

2015

Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.340 Biomarker BEFREE These data may define subsets of glioblastoma that might be sensitive (Dll4(+) /Jag1(+) ) or resistant (Dll4(+) /Jag1(-) ) to bevacizumab. 22296176

2012

Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.340 Biomarker CTD_human Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. 21127729

2010