Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 AlteredExpression BEFREE CD73, an enzyme responsible for adenosine (ADO) production, is overexpressed in cancer cells and emerges as a target for glioblastoma treatment. 31407144

2020
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker BEFREE CD73 inhibition also decreased in vivo rat glioblastoma progression. 30117104

2019
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker BEFREE Interestingly, GBs in CD73-FLK mice were much more invasive and caused complete distortion of the brain morphology. 30926752

2019
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker BEFREE Our analysis demonstrates that CD73 is a negative prognostic factor for GBM and that presence of NK cells may associate with improved prognosis. 31547570

2019
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 Biomarker BEFREE We determined the percentage of cells coexpressing GA-hMSC markers CD105+/CD73+/CD90+ from patients with newly diagnosed high-grade glioma and analyzed the association between this percentage and overall survival (OS) in 3 independent cohorts: fresh surgical glioblastoma specimens (cohort 1, N = 9), cultured tumor specimens at passage 3 (cohort 2, N = 28), and The Cancer Genome Atlas (TCGA) database. 28453745

2017
Entrez Id: 4907
Gene Symbol: NT5E
NT5E
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme 		0.060 AlteredExpression BEFREE In this study, we identify a high expression of CD73 in surgically resected samples of human GBM. 22833450

2013