Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.040 Biomarker BEFREE Our results indicate that low PFKFB3 to PFKFB4 expression ratio is a poor prognostic factor in patients with IDH-wildtype primary glioblastoma and that PFKFB3 and PFKFB4 might represent promising targets for astrocytoma and glioblastoma treatment. 31369092

2019

Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.040 Biomarker BEFREE Here, we studied the mechanisms connecting TGF-β1, glucose metabolism, and PFKFB3 in glioblastoma cell lines. 28834297

2017

Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.040 AlteredExpression BEFREE The PFKFB3 LOH as well as the resulting low UBI2K4 expression level was associated with a poor prognosis of glioblastoma patients. 21987444

2011

Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.040 AlteredExpression BEFREE The effect of transient and stable overexpression of the PFKFB3 isoforms was studied in U87 glioblastoma cells by MTT, cell counting, clone formation assay and metabolic measurements. 19490427

2009