DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Glioblastoma Multiforme ×

Gene: LZTR1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	8216
Gene Symbol:	LZTR1

LZTR1

CUI:	C1621958
Disease:	Glioblastoma Multiforme

Glioblastoma Multiforme

0.330

Biomarker

BEFREE

LZTR1 is also a driver gene in non syndromal glioblastoma.

30664951

2020

Entrez Id:	8216
Gene Symbol:	LZTR1

LZTR1

CUI:	C1621958
Disease:	Glioblastoma Multiforme

Glioblastoma Multiforme

0.330

GeneticVariation

BEFREE

Mutations in LZTR1 have been identified in glioblastoma, schwannomatosis, and Noonan syndrome.

31337872

2020

Entrez Id:	8216
Gene Symbol:	LZTR1

LZTR1

CUI:	C1621958
Disease:	Glioblastoma Multiforme

Glioblastoma Multiforme

0.330

GeneticVariation

BEFREE

On a somatic point of view, LZTR1 mutations are known to drive with a significant frequency glioblastoma (GB) development.

31128261

2019

Entrez Id:	8216
Gene Symbol:	LZTR1

LZTR1

CUI:	C1621958
Disease:	Glioblastoma Multiforme

Glioblastoma Multiforme

0.330

Biomarker

CTD_human

The integrated landscape of driver genomic alterations in glioblastoma.

23917401

2013