Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C1658953
Disease: tumor vasculature
tumor vasculature
0.030 AlteredExpression BEFREE Notably, diosmetin induced the normalization of tumor vasculature through the downregulation of angiopoietin-2 and the improvement of pericyte coverage, leading to suppression of metastasis formation in lungs and lymph nodes. 31228803

2019

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C1658953
Disease: tumor vasculature
tumor vasculature
0.030 AlteredExpression BEFREE VEGFR2 inhibition normalized tumor vasculature whereas ectopic expression of Ang-2 diminished the beneficial effects of VEGFR2 blockade by inhibiting vessel normalization. 20501615

2010

Entrez Id: 285
Gene Symbol: ANGPT2
ANGPT2
CUI: C1658953
Disease: tumor vasculature
tumor vasculature
0.030 Biomarker BEFREE Although endogenous Ang-2 cooperates with vascular endothelial growth factor (VEGF) to protect tumor endothelial cells, the effect on tumor vasculature of high levels of exogenous Ang-2 with different levels of VEGF has not been studied in detail. 17440098

2007