Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10544
Gene Symbol: PROCR
PROCR
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis
0.030 GeneticVariation BEFREE Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients. 23881209

2013

Entrez Id: 10544
Gene Symbol: PROCR
PROCR
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis
0.030 Biomarker BEFREE These results suggest that the EPCR- and PAR-1-dependent protective effects of APC in severe sepsis may partially be mediated through the inhibition of HMGB1 signaling and that the chimeric thrombin mutant has potential therapeutic utility for severe sepsis. 21849480

2011

Entrez Id: 10544
Gene Symbol: PROCR
PROCR
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis
0.030 GeneticVariation BEFREE TNF-alpha 308 G/A, PAI-1 4G/4G, and EPCR mutations influence the risk of severe sepsis in children. 16444434

2006