Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		0.020 Biomarker BEFREE These results suggest that the EPCR- and PAR-1-dependent protective effects of APC in severe sepsis may partially be mediated through the inhibition of HMGB1 signaling and that the chimeric thrombin mutant has potential therapeutic utility for severe sepsis. 21849480

2011
Entrez Id: 2149
Gene Symbol: F2R
F2R
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		0.020 Biomarker BEFREE Protease activated receptor-1 (PAR1) mediates barrier protective signalling of activated protein C (APC) in human endothelial cells in vitro and may contribute to APC's beneficial effects in patients with severe sepsis. 19350118

2009