Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 Biomarker BEFREE An ESR above 106.5 mm/h is associated with increased VTE occurrence. 30965330

2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 Biomarker BEFREE On univariate analysis, older age (RR 1.162, p=0.007), sinus disease (RR 2.62, p=0.05), longer hospital stay (RR 1.03, p<0.001), higher ESR (RR 1.02, p=0.03) and CRP (RR 1.07, p=0.007), and an absence of systemic steroids (RR 0.19, p=0.004) increased the risk of VTE. 28934665

2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 Biomarker BEFREE To test whether estrogen receptor polymorphisms modify the effects of postmenopausal hormone therapy on biomarkers and on risk of coronary heart disease events, stroke, or venous thromboembolism. 21106950

2011
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 GeneticVariation BEFREE Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy. 19082882

2009
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 GeneticVariation BEFREE The relationship between VTE and c.454-397 T>C ER alpha polymorphism was consistent with a dominant model in women and a recessive model in men. 16762402

2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.050 GeneticVariation LHGDN The relationship between VTE and c.454-397 T>C ER alpha polymorphism was consistent with a dominant model in women and a recessive model in men. 16762402

2007