Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE
0.040 AlteredExpression BEFREE We investigated the in vitro ability of four such oligomers to reduce the expression of Notch2 gene in peripheral blood mononuclear cells from B-CLL patients. 22161246

2012

Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE
0.040 AlteredExpression BEFREE These data indicate that downregulation of CD23 and loss of Notch2 activity are early steps in PI-induced apoptosis of B-CLL lymphocytes and may be part of the full apoptotic response. 15565166

2005

Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE
0.040 AlteredExpression BEFREE Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia. 15621797

2005

Entrez Id: 4853
Gene Symbol: NOTCH2
NOTCH2
CUI: C1868683
Disease: B-CELL MALIGNANCY, LOW-GRADE
B-CELL MALIGNANCY, LOW-GRADE
0.040 AlteredExpression BEFREE Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia. 11986231

2002