Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 AlteredExpression BEFREE Serum ADA activity is significantly attenuated in patients with CAD, particularly in MI. 31839921

2019

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 Biomarker BEFREE ACEI = angiotensin-converting enzyme inhibitors; ADA = American Diabetes Association; ARB = angiotensin-receptor blocker; CAD = coronary artery disease; Cr = creatinine; CVD = cardiovascular disease; DM = diabetes mellitus; HF = heart failure; HT = hypertension; JNC = Joint National Committee; KAUH = King Abdullah University Hospital; LV = left ventricular; PAD = peripheral artery disease; RAAS = renin-angiotensin-aldosterone system; TIA = transient ischemic attack. 28816537

2017

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 AlteredExpression BEFREE There have been reports of increased activity of the adenosine deaminase enzyme in individuals with coronary heart disease and DM. 24836059

2014

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 Biomarker BEFREE The fact that the association of ACP1 with CAD is evident only in diabetic subjects, whereas the association of ADA1 with CAD is evident only in nondiabetic subjects suggests an heterogeneity in the pathogenetic mechanisms leading to CAD. 20581655

2010

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 GeneticVariation LHGDN Adenosine deaminase genetic polymorphism and coronary artery disease. 18560234

2009

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 Biomarker BEFREE Twenty-five ADA*1/*2 heterozygotes (12.5%) and 2 ADA*2/*2 homozygotes (1%) were found in the control group, while only 10 *1/*2 heterozygotes (5.9%) and no *2/*2 homozygotes were found in the CAD group. 17287605

2007

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.060 GeneticVariation LHGDN Twenty-five ADA*1/*2 heterozygotes (12.5%) and 2 ADA*2/*2 homozygotes (1%) were found in the control group, while only 10 *1/*2 heterozygotes (5.9%) and no *2/*2 homozygotes were found in the CAD group. 17287605

2007