Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 GeneticVariation BEFREE Although t(3;5)(q25.1;q34) or the NPM1/MLF1 rearrangement has been reported mostly as a sole karyotypic abnormality in younger patients, it should also be considered in elderly patients with complex chromosomal abnormalities in acute myeloid leukemia or myelodysplastic syndrome. 20471513

2010

Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 Biomarker BEFREE The MLF1 and RARA genes are fused with NPM1 in myelodysplastic syndrome and acute myeloid leukemia (AML) with t(3;5) and acute promyelocytic leukemia with t(5;17), respectively. 16984370

2006

Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 AlteredExpression BEFREE Elevated MLF1 expression correlates with malignant progression from myelodysplastic syndrome. 11021751

2000

Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 Biomarker BEFREE Apoptosis induced by the myelodysplastic syndrome-associated NPM-MLF1 chimeric protein. 10391679

1999

Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 GeneticVariation BEFREE MNDA binds NPM/B23 and the NPM-MLF1 chimera generated by the t(3;5) associated with myelodysplastic syndrome and acute myeloid leukemia. 9328447

1997

Entrez Id: 4291
Gene Symbol: MLF1
MLF1
CUI: C3900098
Disease: Adult Myelodysplastic Syndrome
Adult Myelodysplastic Syndrome
0.060 GeneticVariation BEFREE A fusion gene between nucleophosmin (NPM) and myelodysplasia/myeloid leukemia factor 1 (MLF1) is formed by a recurrent t(3;5)(q25.1;q34) in myelodysplastic syndrome and acute myeloid leukemia. 8661158

1996