Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 Biomarker BEFREE Genetic variability in key genes in prostaglandin E2 pathway (COX-2, HPGD, ABCC4 and SLCO2A1) and their involvement in colorectal cancer development. 24694755

2014

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 AlteredExpression BEFREE Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD). 24760190

2014

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 AlteredExpression BEFREE Patients with low 15-PGDH expression in normal-appearing mucosa also demonstrated more advanced stage colorectal cancer (P = 0.045). 23960441

2013

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 AlteredExpression BEFREE Effect of ginger root on cyclooxygenase-1 and 15-hydroxyprostaglandin dehydrogenase expression in colonic mucosa of humans at normal and increased risk for colorectal cancer. 23222413

2013

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 GeneticVariation BEFREE Association of hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) variants and colorectal cancer risk. 21047993

2011

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 Biomarker BEFREE Repression of 15-hydroxyprostaglandin dehydrogenase involves histone deacetylase 2 and snail in colorectal cancer. 19010907

2008

Entrez Id: 3248
Gene Symbol: HPGD
HPGD
Malignant neoplasm of colon and/or rectum
0.070 AlteredExpression BEFREE 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. 15542609

2005