Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 Biomarker BEFREE Thus, our study suggests that repressor activator protein 1 is a prognostic marker and a potential target for colorectal cancer therapy. 28381157

2017
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 Biomarker BEFREE Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer. 27065323

2016
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 GeneticVariation BEFREE C-Jun has been proved as playing an important role in the pathogenesis of tumors, as a main component of Activator protein 1 and c-Jun gene polymorphisms are associated with colorectal cancer. 22489574

2012
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 AlteredExpression BEFREE Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo. 21418301

2011
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 Biomarker BEFREE Src induces urokinase receptor gene expression and invasion/intravasation via activator protein-1/p-c-Jun in colorectal cancer. 17510314

2007
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 Biomarker BEFREE Here, we demonstrate the biological properties of AP-1 and its role in colorectal cancer, and discuss a possibility of an AP-1 inhibitor, an adenovirus dominant-negative mutant of c-Jun, as a therapeutic agent for gene therapy. 16259733

2005
Entrez Id: 3726
Gene Symbol: JUNB
JUNB
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.070 Biomarker BEFREE To investigate the role of AP-1 in colorectal cancer, we constructed an adenovirus-expressing TAM67, a dominant-negative mutant of c-Jun lacking the transactivation domain of wild c-Jun (DN-c-Jun), to inhibit endogenous AP-1. 14712303

2004