×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
EpCAM Aptamer-Functionalized Cationic Liposome-Based Nanoparticles Loaded with miR-139 -5p for Targeted Therapy in Colorectal Cancer .
31589818 2019
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
MicroRNA-139 -5p regulates chronic inflammation by suppressing nuclear factor-κB activity to inhibit cell proliferation and invasion in colorectal cancer .31616518 2019
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Long noncoding RNA HCP5 contributes to epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation and interacting with miR-139 -5p.
30899394 2019
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
miR-139 could be a potential biomarker for diagnosis of digestive system tumors especially colorectal cancer .29883634 2018
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Our results showed that miR-139 -3p was silenced whereas miR-622 was overexpressed in colorectal cancer .
28404964 2017
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
MiR-139 -5p as a novel serum biomarker for recurrence and metastasis in colorectal cancer .28262692 2017
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
miR-139 -5p sensitizes colorectal cancer cells to 5-fluorouracil by targeting NOTCH-1.27173050 2016
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Given this insight into the miRNA regulation of MDR, miR-139 -5p could be a promising therapeutic target for colorectal cancer therapy.
27738333 2016
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
miR-139 -5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2.27244080 2016
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
MiR-139-5p (denoted thereafter as miR-139 ) has recently been reported to function as a tumor suppressor in several types of human cancer (hepatocellular carcinoma, colorectal cancer , breast cancer, and gastric cancer), but its function in non-small-cell lung cancer (NSCLC) and the mechanism of its suppression have not been studied in detail.
26256448 2015
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
microRNA-139 -5p exerts tumor suppressor function by targeting NOTCH1 in colorectal cancer .24885920 2014
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Here, we describe post-transcriptional regulation of this intronic microRNA in human colorectal cancer . miR-139 -5p is expressed independently of its overexpressed host gene PDE2A in colorectal cancer tissues and cell lines.
24942287 2014
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Gene module based regulator inference identifying miR-139 as a tumor suppressor in colorectal cancer .
25286864 2014
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
MiR-139 -5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1.25149074 2014
×
Entrez Id: 406931
Gene Symbol: MIR139
MIR139
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
MiR-139 inhibits invasion and metastasis of colorectal cancer by targeting the type I insulin-like growth factor receptor.22580051 2012