Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C4725671
Disease: High-Risk Neuroblastoma
High-Risk Neuroblastoma 		0.010 Biomarker BEFREE Ectopic up-regulation of PTPRD in neuroblastoma dephosphorylates tyrosine residues in AURKA resulting in a destabilization of this protein culminating in interfering with one of AURKA's primary functions in neuroblastoma, the stabilization of MYCN protein, the gene of which is amplified in approximately 25 to 30% of high risk neuroblastoma. 22305495

2012