Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
estrogen receptor-negative breast cancer
0.030 Biomarker BEFREE Collectively, we conclude that HBXIP induces PKM2 through transcription factor E2F1 to facilitate ER+ breast cancer cell proliferation. 29925919

2019

Entrez Id: 1869
Gene Symbol: E2F1
E2F1
estrogen receptor-negative breast cancer
0.030 AlteredExpression BEFREE Depletion of E2F-1 and MAD1 by using siRNA reversed the pEGCG downregulated hTERT expression and associated cellular apoptosis differently in ER-positive and ER-negative breast cancer cells. 21411498

2011

Entrez Id: 1869
Gene Symbol: E2F1
E2F1
estrogen receptor-negative breast cancer
0.030 AlteredExpression BEFREE We also demonstrated, by adenovirus vector-mediated RNA interference, that ACTR is required for E2F1-mediated gene expression and the proliferation of estrogen receptor (ER)-negative breast cancer cells. 15169882

2004