Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 GeneticVariation BEFREE The p53 codon 249 mutant--derived from human functional adrenal tumors--can modify the cell shape of normal adrenocortical transfected cells. 11448536

2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 Biomarker BEFREE Molecular analysis of CDKN1C and TP53 in sporadic adrenal tumors. 11454518

2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 Biomarker BEFREE To explore the clinical significance of p53 in the pathogenesis of adrenal neoplasms, we investigated the incidence of p53 gene mutations in functioning human adrenal tumours using the polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique to screen p53 exons 4 to 9. 9795365

1998
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 GeneticVariation BEFREE It is possible that the differences in p53 protein and/or mRNA contents reflect corresponding differences in the pathogenetic importance of p53 alterations in these types of adrenal tumors. 9972675

1998
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 GeneticVariation BEFREE A significant decrease of the transcriptional activity of p53 mutants deriving from human functional adrenal tumors. 8892752

1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 GeneticVariation BEFREE No evidence was found for mutations in exons 4-9 of the p53 gene in these varieties of adrenal tumours. 8800591

1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 Biomarker BEFREE Detection of p53 in the adrenal tumor by immunostaining suggested that the mutant protein was expressed. 7614454

1995
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0001624
Disease: Adrenal Gland Neoplasms
Adrenal Gland Neoplasms 		0.380 GeneticVariation BEFREE These findings suggest that the p53 gene mutation may play a role in the tumorigenesis of benign and functional human adrenal tumors. 8106638

1994