Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 AlteredExpression BEFREE The results suggest that general upregulation of GLI‑1 does not seem to be a feature of the disease and are in line with modest biological and clinical effects observed with inhibitors of Hedgehog signaling pathway in patients with myelofibrosis. 31712882

2019
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker BEFREE Therefore, targeting Gli proteins directly might be an interesting and novel therapeutic approach in MF. 29572380

2018
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 AlteredExpression BEFREE The same pathway is also active in human BMF, and Gli1 expression in BMF significantly correlates with the severity of the disease. 28457748

2017