Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.050 Biomarker BEFREE Notch, K-Ras, IL-8, and apoptosis pathways were altered the most in PMF as compared with controls. 31678370

2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.050 AlteredExpression BEFREE Serum levels of interleukin-8 (IL-8) and lymphoid-associated activation markers - soluble interleukin-2 receptor (sIL-2R) and immunoglobulin-free light chains (FLC) - were evaluated in patients with primary myelofibrosis (MF), post-polycythemia vera MF, and post-essential thrombocythemia MF, and compared with the levels in healthy donors. 28946149

2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.050 AlteredExpression BEFREE We found that mRNA levels of interleukin-8, one of the candidate cytokines related to the pathogenesis of myelofibrosis, was elevated predominantly in megakaryocytes derived from MF-iPS. 24859480

2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.050 Biomarker BEFREE Circulating levels of MCP-1, sIL-2R, IL-15, and IL-8 predict anemia response to pomalidomide therapy in myelofibrosis. 21442636

2011
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.050 Biomarker BEFREE IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis. 15454487

2005