Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker BEFREE The majority of cytokines elevated in MF exhibited ex vivo hypersensitivity to thrombopoietin (TPO), toll-like receptor (TLR) ligands, and/or tumor necrosis factor (TNF). 30718771

2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker BEFREE The proportions of TNF-α<sup>+</sup> and IL-6<sup>+</sup> B cells were elevated in myelofibrosis patients. 31297883

2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis 		0.030 Biomarker BEFREE Blockade of TNF receptor 2 (TNFR2), but not TNFR1, selectively inhibited colony formation by MF CD34<sup>+</sup> and mouse JAK2<sup>V617F</sup> progenitor cells. 29749399

2018