Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 100187907
Gene Symbol: TRAP
TRAP
CUI: C0002382
Disease: Alveolar Bone Loss
Alveolar Bone Loss 		0.020 Biomarker BEFREE Alveolar bone loss was clinically measured and TRAP+ osteoclasts, osteoblastic activity, and MMP-1 expression were examined histologically. 30758401

2019
Entrez Id: 100187907
Gene Symbol: TRAP
TRAP
CUI: C0002382
Disease: Alveolar Bone Loss
Alveolar Bone Loss 		0.020 Biomarker BEFREE For both WT and TLR9 KO mice, CpG significantly induced B cell proliferation, increased IL-10 mRNA expression and protein secretion of IL-10 but reduced CD1dhiCD5+ B cells population; local injection of CpG+CD40L mixture significantly decreased alveolar bone loss and the number of TRAP-positive cells adjacent to the alveolar bone surface, and significantly increased the gingival mRNA expression of IL-10 and decreased RANKL and IFN-γ mRNA expression. 29791566

2018