DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Alveolar Bone Loss ×

Gene: TM7SF2 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	7108
Gene Symbol:	TM7SF2

TM7SF2

CUI:	C0002382
Disease:	Alveolar Bone Loss

Alveolar Bone Loss

0.010

Biomarker

BEFREE

In vivo, Ang-(1-7) and DIZE decreased alveolar bone loss through improvement of osteoblast/osteoclast ratio.A-779 reversed such phenotype.

2019