Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 AlteredExpression BEFREE Increased CLEC-2 and zonulin levels were observed in MCI and AD patients. 31715011

2020
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 Biomarker BEFREE Screening a specific Zn(ii)-binding peptide for improving the cognitive decline of Alzheimer's disease in APP/PS1 transgenic mice by inhibiting Zn<sup>2+</sup>-mediated amyloid protein aggregation and neurotoxicity. 31588929

2019
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 Biomarker BEFREE In addition, Hp may correlate with the severity of AD. 29325993

2018
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 Biomarker BEFREE Haptoglobin is here reported to form a complex with beta-amyloid as shown by immunoblotting experiments with purified proteins, or by its immunoprecipitation in brain tissues from patients with Alzheimer's disease. 25058565

2014
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 Biomarker BEFREE Increases in cerebrospinal fluid (CSF) levels of the acute phase protein haptoglobin (Hp) occur in central nervous system (CNS) disorders such as Alzheimer's disease. 11323115

2001
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE We failed to find a significant association between either of the Hp alleles and DAT. 3699841

1986
Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.070 GeneticVariation BEFREE C3 and haptoglobin polymorphism in dementia of the Alzheimer type. 6702477

1984