Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.040 AlteredExpression BEFREE Methotrexate attenuates the Th17/IL-17 levels in peripheral blood mononuclear cells from healthy individuals and RA patients. 21691744

2012
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.040 Biomarker BEFREE (2) The percentage and MFI of peripheral CD4(+) IL-17(+) cells in RA patients were significantly higher comparing to normal controls (1.64 ± 0.97% vs. 0.75 ± 0.20%, p < 0.01; and 29.8 ± 9.7 vs. 19.8 ± 4.6, p < 0.05, respectively), and positively correlated with ESR and DAS28. 19847432

2010
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.040 Biomarker BEFREE Modest evidence of an association with IL17A in Norwegian RA patients was observed. 19208686

2009
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.040 AlteredExpression BEFREE IL-6/sIL-6R directly induced RANKL expression in RA-FLS and it is essential for RANKL induction by TNF-alpha and IL-17. 18786965

2008