Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.050 GeneticVariation BEFREE Moreover, we also observed that Foxp3 serum levels were higher, and RORc2 serum levels were lower in RA patients with rs12434439 GG. 29411043

2018
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.050 AlteredExpression BEFREE The induced Foxp3 expression was independent of retinoic acid (RA) signaling but was inhibited by neutralization of TGF-β. 28750075

2017
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.050 Biomarker BEFREE The present study provides the first evidence of increased CD25(-)FOXP3(+) cells in RA patients, which were associated with disease activity and with GC treatment in carriers of the high IL-10 genotype, suggesting that this population plays a role in the clinical response to prednisone in RA. 22447883

2012
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.050 AlteredExpression BEFREE We provide evidence of an increased expression of FoxP3 splice forms in synovial CD4+ T cells from RA patients. 22515293

2012
Entrez Id: 50943
Gene Symbol: FOXP3
FOXP3
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.050 AlteredExpression BEFREE Peripheral FoxP3 mRNA expression in active RA patients was significantly lower comparing to normal controls, and negatively correlated with ESR. 19847432

2010