Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis 		0.050 Biomarker BEFREE APOE ε2 is a strong genetic determinant of low lipoprotein(a) concentrations but does not modify the causal association of lipoprotein(a) with myocardial infarction or aortic valve stenosis. 28651346

2017
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis 		0.050 GeneticVariation BEFREE Apolipoprotein E alleles and bicuspid aortic valve stenosis in monozygotic twins. 19304773

2009
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis 		0.050 Biomarker BEFREE APOE e4 is not associated with AS, reflecting the different genetic backgrounds of CAD and AS. 16606866

2006
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0003507
Disease: Aortic Valve Stenosis
Aortic Valve Stenosis 		0.050 GeneticVariation BEFREE Given the risk factor and histological similarities between coronary and calcific valvular heart disease (aortic stenosis [AS] and mitral annular calcification [MAC]), we postulated that apoE alleles might be associated with the development of these valvular lesions. 14530190

2003