Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.050 Biomarker BEFREE Akt isoforms play key roles in multiple cellular processes; however, the roles of Akt-1 and Akt-2 isoforms in the development of T cell-mediated autoimmunity are poorly defined. 30692211

2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.050 GeneticVariation BEFREE Increasing body of data suggests that alterations in the PI3K/AKT/mTOR pathway may result in an enhanced susceptibility to autoimmunity. 29492193

2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.050 Biomarker BEFREE AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease. 27312110

2016
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.050 AlteredExpression BEFREE CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance. 24667640

2014
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases 		0.050 Biomarker BEFREE The antigens are derived from various genes including a chimeric gene between E-cadherin and an unknown gene Y, AKT oncogene, genes overexpressed in stomach cancers, genes of which the transcripts are alternatively or aberrantly spliced, and genes known to be involved in autoimmune diseases. 10950146

2000