Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 GeneticVariation BEFREE The index case and the two daughters with Behçet-like disease, were previously found to have a TNFAIP3 frameshift mutation. 31376265

2020
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 Biomarker BEFREE It has recently been recognized that TNFAIP3 deficiency leads to early onset of autoinflammatory and autoimmune syndrome resembling Behçet's disease. 30810840

2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 Biomarker BEFREE Genetic screening of TNFAIP3 should be considered for familial BD-like patients with early-onset recurrent fevers. 31164164

2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 GeneticVariation BEFREE Further functional studies are required to research whether the variant of TNFAIP3 plays a part in the development of GPP or simply causes the Behçet's disease phenotype. 31353537

2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 GeneticVariation BEFREE Mutations in tumor necrosis factor α-induced protein 3 results in a disease that can present as Behçet disease called haploinsufficiency of A20. 28582318

2017
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 Biomarker BEFREE Lack of association of TNFAIP3 and JAK1 with Behçet's disease in the European population. 26005883

2016
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 Biomarker BEFREE These associations include ERAP1, CCR1-CCR3, STAT4, KLRC4, GIMAP4, and TNFAIP3 in Behçet's disease; BLK and CD40 in Kawasaki disease; SERPINA1 and SEMA6A in antineutrophil cytoplasmic antibody associated vasculitides; IL12B and FCGR2A/ FCGR2A in Takayasu arteritis; and CECR1 in a newly defined vascular inflammatory syndrome associated with adenosine deaminase (ADA2) deficiency. 25405820

2015
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 GeneticVariation BEFREE The aim of the study was to investigate the association of TNFα-induced protein 3 interacting with protein 1 (TNIP1) gene polymorphisms with Vogt-Koyanagi-Harada (VKH) syndrome and Behcet's disease (BD) in a Han Chinese population. 24788730

2014
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0004943
Disease: Behcet Syndrome
Behcet Syndrome 		0.090 GeneticVariation BEFREE TNFAIP3 gene polymorphisms confer risk for Behcet's disease in a Chinese Han population. 23161053

2013