Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.050 Biomarker BEFREE Cathepsin X is a cysteine peptidase involved in the progression of cancer and neurodegenerative diseases. 28904354

2017
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.050 AlteredExpression BEFREE Cathepsin X, a cysteine carboxypeptidase, is upregulated in several types of cancer. 26325675

2015
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.050 Biomarker BEFREE The lysosomal cysteine carboxypeptidase cathepsin X (CTSX), localized predominantly in immune cells, has been associated with the development and progression of cancer. 25442015

2014
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.050 Biomarker BEFREE Cathepsin X has been reported to be a tumor promotion factor in various types of cancer; however, the molecular mechanisms linking its activity with malignant processes are not understood. 23326535

2013
Entrez Id: 1522
Gene Symbol: CTSZ
CTSZ
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.050 AlteredExpression BEFREE The cysteine-type peptidase cathepsin X is highly upregulated in several cancers and presumably promotes tumor invasion through bypassing cellular senescence. 23152410

2012