Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 Biomarker BEFREE Taken together, these data suggest that AATF may serve as a drug target to treat KRAS-driven malignancies. 29321668

2018
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 Biomarker BEFREE Here, we have shown that AATF genome encoded miR-2909, known to play role both in immunity and cancer upregulates various interferon stimulating genes (ISGs) including ISGylation system through STAT1. 28622443

2017
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 Biomarker BEFREE Che-1/AATF is a potential therapeutic target for cancer treatments. 29232376

2017
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 AlteredExpression BEFREE Che-1 can also regulate mutant p53 expression, which plays roles in many types of cancer. 27012205

2016
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 GeneticVariation BEFREE This mutant AATF along with its interactome consisting of SP1, DNMT3B and Par-4 ensures cancer cell DNA methylation required for down-regulation of tumor suppressor genes. 25231211

2015
Entrez Id: 26574
Gene Symbol: AATF
AATF
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.060 GeneticVariation BEFREE Here we have screened the entire coding region of AATF in affected index cases from 121 Finnish cancer families for germline defects, using conformation sensitive gel electrophoresis and direct sequencing. 20025740

2009