Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE TRAF2 Cooperates with Focal Adhesion Signaling to Regulate Cancer Cell Susceptibility to Anoikis. 30373932

2019
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE The RANK-c-mediated inhibition of cancer cell aggressiveness and nuclear factor-κB (NF-κB) activation in breast cancer cells seems to rely on a RANK-c/TNF receptor-associated factor-2 (TRAF2) protein interaction. 29844572

2018
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE BACKGROUND TRAF2 exerts important functions in regulating the development and progression of cancer. 28855498

2017
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE TRAF2 promotes cancer cell survival, proliferation and metastasis through the NF-κB pathway by directly interacting with various TNF recepors. 24677135

2014
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE In addition, TRAF2 is overexpressed in colon cancer and required for colon cancer development, suggesting that TRAF2 might be a potential molecular target for cancer prevention and treatment. 22685297

2012
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 AlteredExpression BEFREE The treated cancer tissues showed an enhanced apoptosis and the decreased TRAF2 level. 22532625

2012
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE These results also support LMP1, LMP2A, and TRAF2 as potential therapeutic targets in a subset of EBV-associated lymphoid malignancies. 18230756

2008
Entrez Id: 7186
Gene Symbol: TRAF2
TRAF2
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.080 Biomarker BEFREE Further support for the role of TRAF2 in cancer comes from the observations that TRAF2 is overexpressed in both lung adenocarcinoma tissues and multiple lung cancer cell lines. 18794145

2008