Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker BEFREE PDK-1 silence resulted in the inhibition of NSCLC cell survival. 30988063

2019
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker BEFREE Collectively, we observe that BBR inhibits proliferation of NSCLC cells through inhibition of SP1 and PDPK1; this results in a reduction of DNMT1 expression. 28840963

2018
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker BEFREE These findings suggest that miR-138 as a potential tumor suppressor could inhibit cell proliferation by targeting PDK1 in NSCLC cells, which could be employed as a potential therapeutic target for miRNA-based NSCLC therapy. 24405893

2015
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker BEFREE More importantly, miR-138 and PDK1 may synergistically predict patients' prognosis and their combination may represent a promising prognostic biomarker of human NSCLC. 25064732

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 AlteredExpression BEFREE We showed that NAC inhibited NSCLC cell proliferation through reduction of PDK1 expression. 23867003

2013