Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 Biomarker BEFREE Our data suggested MEG3 was involved in stem cell-like state of LCCs and curbed migration and invasion through miR-650/SLC34A2 axis in NSCLC. 31585300

2019
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE All these experiments were designed to investigate whether lncRNA MEG3 participated in the pathogenesis of NSCLC through inhibiting the expression of BRCA1 and Bcl-2 and promoting Bax expression. 30280775

2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE PTX significantly inhibited the proliferation of NSCLC cells and increased the expressions of MEG3 and P53. 30173893

2018
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 Biomarker BEFREE Mouse NSCLC transplanted tumor was established to verify the functional role of MEG3 in DDP resistance in vivo. 29123412

2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE However, the association between MEG3 expression and prognosis in non-small cell lung cancer (NSCLC) has not been fully investigated. 28782577

2017
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE In this study, we identified the expressing difference of several tumor-related lncRNAs in breast cancer samples and found that, MEG3, which is downregulated in non-small cell lung cancer (NSCLC) tumor tissues, is also downregulated in breast cancer samples compared with adjacent tissues. 27166155

2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 Biomarker BEFREE We therefore performed a meta-analysis on six lncRNAs (PVT1, AFAP1-AS1, LINC01133, ANRIL, MEG3 and UCA1) to clarify their prognostic roles in NSCLC. 27833074

2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE The levels of Meg3 and Skp2 were inversely correlated in NSCLC specimens. 26482610

2016
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 Biomarker BEFREE In conclusion, these results suggested that Meg3 may have a crucial role in the development of cisplatin resistance in non-small cell lung cancer. 26059239

2015
Entrez Id: 55384
Gene Symbol: MEG3
MEG3
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.100 AlteredExpression BEFREE NSCLC cells transfected with pCDNA-MEG3 were injection into nude mice to study the effect of MEG3 on tumorigenesis in vivo . 24098911

2013