Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 Biomarker BEFREE The p-GSK3β (Ser9) protein level in Caki-2 cells was significantly down-regulated, while the DNA fragmentation rate increased after treatment with 5 μM DAC at 96 h. Our data show that sFRP2 functions as a tumor suppressor gene in RCC and that its restoration may offer a new therapeutic approach for the treatment of RCC. 23975733

2013
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 Biomarker BEFREE Our study was designed to elucidate the silencing mechanism of sFRP2 in RCC. 18404682

2008
Entrez Id: 6423
Gene Symbol: SFRP2
SFRP2
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.330 Biomarker BEFREE Samples (n = 62) of RCC and corresponding normal renal tissue (NRT) were analyzed using methylation-specific PCR for methylation of six Wnt antagonist genes (sFRP-1, sFRP-2, sFRP-4, sFRP-5, Wif-1, and Dkk-3). 17145819

2006