Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer. 31093274

2019
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE Then, we found that the protein ITGA5 was identified as a binding partner of FN1 and ITGA5 overexpression reversed FN1-induced tumorigenesis of CRC in vitro. 29274284

2018
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE We evaluated the significance of vimentin and fibronectin gene expression in relation to invasion and metastasis in CRC patients. 28900381

2017
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 Biomarker BEFREE In addition, fibronectin mediated Snail and serpinA1 signaling was involved in CRC cell invasion and migration. 26015410

2015
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 Biomarker BEFREE We have demonstrated previously that CRC-derived fibronectin extra domain A (EDA) promotes vasculogenesis, tumorigenesis and metastasis of CRCs. 24743511

2014
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 GeneticVariation BEFREE A single nucleotide polymorphism in fibronectin 1 determines tumor shape in colorectal cancer. 24919860

2014
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE The extra domain A of fibronectin increases VEGF-C expression in colorectal carcinoma involving the PI3K/AKT signaling pathway. 22496919

2012
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE The introduction of major EMT regulators (Slug and Twist) into CRC cell lines reduced the levels of E-cadherin and induced fibronectin and vimentin, but unlike L1, Slug and Twist expression was insufficient for conferring metastasis. 21123622

2011
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE Thus, expression of FZD7 in colorectal cancer may be regulated by fibronectin in the microenvironment. 19655379

2010
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 Biomarker BEFREE Together, these findings consistently indicate that PPAR-beta may facilitate differentiation and inhibit the cell-fibronectin adhesion of colon cancer, having a role as an inhibitor in the carcinogenesis and progression of colorectal cancer. 19935699

2010
Entrez Id: 2335
Gene Symbol: FN1
FN1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.400 AlteredExpression BEFREE Extracellular matrix proteins in colorectal carcinomas. Expression of tenascin and fibronectin isoforms. 7543628

1995