Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.450 AlteredExpression BEFREE Mice with a coronary artery disease-linked mutation in Wnt-coreceptor LRP6 (LDL receptor-related protein 6) exhibit vascular smooth muscle cell dedifferentiation and obstructive coronary artery disease, which are paradoxically associated with reduced TCF7L2 expression. 30567484

2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.450 Biomarker BEFREE Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease. 26489464

2015
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.450 GeneticVariation BEFREE Moreover, we observed associations between TCF7L2 variants and the following diabetic complications: diabetic retinopathy, cardiovascular disease and coronary artery disease. 22843023

2013
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.450 GeneticVariation BEFREE This study aimed to evaluate the association between TCF7L2 polymorphism rs7903146 and coronary artery disease in diabetic and non-diabetic subjects. 19924244

2009
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.450 GeneticVariation BEFREE TCF7L2 rs7903146 T allele is associated with a 1.57 increased risk for type 2 diabetes in a Brazilian cohort of patients with known coronary heart disease. 19055834

2008