Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0013264
Disease: Muscular Dystrophy, Duchenne
Muscular Dystrophy, Duchenne 		0.040 AlteredExpression BEFREE While dystrophin is expressed in healthy hPSC, its deficiency in DMD hPSC lines induces the release of reactive oxygen species (ROS) through dysregulated activity of all three isoforms of nitric oxide synthase (further abrev. as, NOS). 30650618

2019
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0013264
Disease: Muscular Dystrophy, Duchenne
Muscular Dystrophy, Duchenne 		0.040 AlteredExpression BEFREE These results suggest that the expression of NOS-M in skeletal muscle may be therapeutically beneficial in DMD and other muscle diseases characterized by the loss of nNOSμ from the sarcolemma. 26604149

2016
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0013264
Disease: Muscular Dystrophy, Duchenne
Muscular Dystrophy, Duchenne 		0.040 Biomarker BEFREE According to the prevailing model, nNOS is recruited to the sarcolemma by syntrophin, and in DMD this localization is altered. 19229108

2009
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
CUI: C0013264
Disease: Muscular Dystrophy, Duchenne
Muscular Dystrophy, Duchenne 		0.040 AlteredExpression BEFREE Many reports have documented that very low levels of nNOS protein exist in muscle fibers of Duchenne muscular dystrophy (DMD) patients. 11745948

2001