Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE Hence, we examined the clinical characteristics and the incidence of gastric mucosal injury after CRT for esophageal cancer. 31222680

2019

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE The impact of the neoadjuvant chemoradiation-to-surgery (CRT-S) interval in patients with esophageal cancer is not clear. 30311162

2019

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE Patients with isolated persistent or recurrent EC after initial CRT had similar 5-year OS (14.0% versus 19.7%, difference in proportion -5.7, 95% CI [-13.7; 2.3]). 30447937

2019

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE Influence of 3D-CRT and conformal IMRT on thyroid function of patients with cervical and upper thoracic esophageal cancer and comparison of clinical efficacy. 30867781

2019

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE The aim of this review is to evaluate the radiation dose, fractionation strategies, and predictive factors of response to therapy in functional imaging for definitive chemoradiotherapy in esophageal carcinoma, with an emphasis on seeking the predictive model of response to CRT and trying to individualize the radiation dose for EC patients. 29343986

2018

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE This network meta-analysis showed neoadjuvant CRT followed by surgery to be the most effective strategy in improving survival of resectable esophageal cancer. 27429017

2017

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE This meta-analysis was performed to compare IMRT and 3D-CRT in the treatment of EC in terms of dose-volume histograms and outcomes including survival and toxicity. 28767597

2017

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE Relative change in FDG uptake after 14 days of CRT is not associated with DFS in patients with esophageal cancer undergoing neoadjuvant chemoradiotherapy followed by surgery. 27001344

2017

Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms
0.090 Biomarker BEFREE Radiation combined with chemotherapy (neo-CRT) is increasingly the standard of care for the treatment of esophageal cancer, either as neoadjuvant therapy in multimodal protocols or as primary therapy. 22214381

2012