Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
CUI: C0015544
Disease: Failure to Thrive
Failure to Thrive 		0.120 Biomarker BEFREE Among the deleted genes, HMGA2 is of particular interest in relationship to the aberrant somatic growth in our patient, as HMGA2 variants have been linked to stature variations in the general population and loss of function of Hmga2 in the mouse results in the pygmy phenotype that combines pre and postnatal growth failure, with resistance to the adipogenic effect of overfeeding. 19277063

2009
Entrez Id: 8091
Gene Symbol: HMGA2
HMGA2
CUI: C0015544
Disease: Failure to Thrive
Failure to Thrive 		0.120 GeneticVariation BEFREE We have previously shown that LEMD3 haploinsufficiency is responsible for the Buschke-Ollendorff lesions and now provide strong evidence that a heterozygous deletion of HMGA2 is causing the growth failure observed in this disorder. 19298872

2009