Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 47
Gene Symbol: ACLY
ACLY
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.030 AlteredExpression BEFREE Additionally, hepatic SIRT2 overexpression decreased ACLY-3K acetylation and its protein level and alleviated hepatic steatosis in HF/HS diet-fed mice. 31197036

2019
Entrez Id: 47
Gene Symbol: ACLY
ACLY
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.030 Biomarker BEFREE ACLY is also a target against dyslipidaemia and hepatic steatosis, with a compound currently in phase 3 clinical trials<sup>4,5</sup>. 30944472

2019
Entrez Id: 47
Gene Symbol: ACLY
ACLY
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.030 Biomarker BEFREE Metabolic pathways are built to elucidate the mechanisms by which VIRG host's higher energy requirements were met: including gene up-regulations for intestinal gluconeogenesis (PEPCK) and liver glycolysis (ENO2), and intriguingly liver fatty acid synthesis through ATP citrate synthase (CS) down-regulation and ATP citrate lyase (ACLY) and malic enzyme (ME) up-regulations. 22272335

2012