Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression BEFREE GFAP promoter driven transgenic expression of PDGFB in the mouse brain leads to glioblastoma in a Trp53 null background. 19115382

2009
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression BEFREE The PDGF B-chain was expressed in 5 of 8 glioblastoma cell lines, 2 of 6 glioblastomas, and in 3 of 4 anaplastic astrocytoma explants. 1997889

1991
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 AlteredExpression BEFREE Thus the TGF-beta signal pathway does not involve activation of protein kinase C, and at least two initially distinct intracellular signaling routes lead to activation of c-sis gene expression in this glioblastoma cell line. 2655888

1989
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE Genomic Southern blots of DNA from 7 different cultured human glioblastoma cell lines and 15 different solid human brain tumors revealed no significant change in either the gross structure or the copy number of the c-sis gene in tumor cells vs. control cells. 2585029

1989
Entrez Id: 5155
Gene Symbol: PDGFB
PDGFB
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.050 Biomarker BEFREE Enhanced expression of the human SIS/PDGF-2 gene has been reported in a number of human cell lines, sarcomas, and glioblastomas. 2901834

1988