Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0017638
Disease: Glioma
Glioma 		0.040 GeneticVariation BEFREE Effective treatment for glioma is challenging, which can be in part due to prolonged chemotherapy leading to mutations in genes associated with multi-drug resistances (MRP1, Bcl-2, and ABC family). 31129471

2019
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0017638
Disease: Glioma
Glioma 		0.040 GeneticVariation BEFREE We investigated whether the ABC efflux transporters ABCG2 and ABCB1 expressed in the blood-brain barrier (BBB), are limiting the efficacy of dasatinib in the treatment of glioma using genetic and pharmacologic approaches. 26883271

2016
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker BEFREE Our findings indicate a crucial role of ABCB6 in ALA metabolism and accumulation of PpIX in glioma. 22688660

2013
Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0017638
Disease: Glioma
Glioma 		0.040 Biomarker BEFREE FCH would be an interesting probe for glioma imaging which would not be effluxed from the resistant cells by the classic MDR ABC transporters. 19300998

2009