Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.140 GeneticVariation BEFREE However, subgroup analyses showed that the ABCA1 C69T gene mutation significantly reduced the risk of hypertriglyceridemia in diabetic patients as compared with that in non-diabetic subjects (dominant model: WMD =0.66, 95% CI = 0.52-0.8, P < 0.0001; recessive model: WMD = 0.47, 95%CI = 0.11-0.83, P = 0.01). 31010439

2019
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.140 Biomarker BEFREE Furthermore, the data establish that ABCA1 and apoCIII-containing HDL play key roles in the prevention of apoCIII-induced hypertriglyceridemia in mice. 18767813

2008
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.140 GeneticVariation BEFREE Mutations within the ABCA1 gene are associated with decreased HDL-C, increased triglycerides, and an increased risk of CAD. 11238261

2001
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0020557
Disease: Hypertriglyceridemia
Hypertriglyceridemia 		0.140 GeneticVariation BEFREE ABCA1 heterozygotes have decreased HDL cholesterol (HDL-C) and increased triglycerides. 11086027

2000