Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE NOS3 gene variants and male infertility: Association of 4a/4b with oligoasthenozoospermia. 28466478

2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE eNOS gene T786C, G894T and 4a4b polymorphisms and male infertility susceptibility: a meta-analysis. 27373555

2017
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE Our study provides genetic evidence for the eNOS gene being a risk factor for idiopathic AZS and male infertility. 25505202

2015
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE Of five NOS gene polymorphisms investigated in the present study, we found NOS3 rs1799983 might cause oxidative sperm DNA damage, thereby contributing to male infertility. 25517965

2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE In conclusion, the findings demonstrate that, in Brazilian population studied, genetic variations, T-786C, G894T, and e 4a/b, of the eNOS gene are not associated with male infertility. 23419608

2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE These findings suggested that the variants of eNOS gene may modify the susceptibility to male infertility with impaired spermatogenesis. 23756085

2013
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0021364
Disease: Male infertility
Male infertility 		0.370 GeneticVariation BEFREE Three eNOS polymorphisms were investigated to assess its association with male infertility by pyrosequencing and gel electrophoresis. 18539276

2008