Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0023440
Disease: Acute Erythroblastic Leukemia
Acute Erythroblastic Leukemia
0.050 Biomarker BEFREE ChIP-seq analyses in a human erythroleukemia cell line showed that LYL1 exclusively bound a small subset of SCL targets including <i>GATA1.</i> Together, these data show for the first time that <i>Lyl1</i> can maintain primitive erythropoiesis. 30185409

2018

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0023440
Disease: Acute Erythroblastic Leukemia
Acute Erythroblastic Leukemia
0.050 Biomarker BEFREE mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. 10688671

2000

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0023440
Disease: Acute Erythroblastic Leukemia
Acute Erythroblastic Leukemia
0.050 AlteredExpression BEFREE TAL1 expression by erythroid cells in vivo and in chemical-induced erythroleukemia cell lines in vivo suggested the gene might regulate aspects of erythroid differentiation. 7744799

1995

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0023440
Disease: Acute Erythroblastic Leukemia
Acute Erythroblastic Leukemia
0.050 Biomarker BEFREE Therefore, immunoprecipitation with anti-TAL1 antisera was used to demonstrate the presence of TAL1 phosphoproteins, pp42TAL1 and pp22TAL1, in both T-ALL and erythroleukemia cell lines. 8437851

1993

Entrez Id: 6886
Gene Symbol: TAL1
TAL1
CUI: C0023440
Disease: Acute Erythroblastic Leukemia
Acute Erythroblastic Leukemia
0.050 Biomarker BEFREE To illuminate the function of SCL in the erythroid lineage, an antisense SCL construct was introduced into the human erythroleukaemia cell line, K562. 1756722

1991